Taken from a Nuclear Engineering Seminar:

MONTE CARLO OPTIMIZATION OF THE IN VIVO XRF MEASUREMENT OF LEAD IN BONE

R.P. Gardner, Q. Ao, and S. Lee

This work has been sponsored by the National Institute of Environmental Health Sciences of the National Institutes of Health. The primary purpose of the work is to improve the minimum detectable concentration that is possible with both the K and L XRF methods of in vivo lead measurement in bone. This has been accomplished primarily through the use of a comprehensive Monte Carlo program called CEARXRF developed by the authors for that purpose. The general problem of lead accumulation and in vivo measurement is first discussed. Then the Monte Carlo code CEARXRF is described, an error analysis is performed with it, some techniques for minimizing errors including the Monte Carlo - Library Least-Squares (MCLLS) approach are presented, and a Monte Carlo code called CEARPPU for describing pulse pile-up distortion is presented.

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  Department of Nuclear Engineering
NC State University
Raleigh, North Carolina